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If Osty is alive, he dies and you gain Block equal to double his Max HP.
Sacrifice is the ultimate defensive payoff for Summon-heavy decks, converting Osty's accumulated Max HP into a massive Block shield. It is most effective in boss fights to negate massive incoming attacks after spending several turns scaling Osty's size with Summon cards.
Reanimate
This card provides a massive boost to Osty's Max HP, which directly doubles the Block yield of Sacrifice while also serving as a way to quickly revive him after he is consumed.
Protector
Both cards scale directly with Osty's Max HP, allowing the player to build a deck where the same Summon engine provides both extreme offensive damage and extreme defensive Block.
Phylactery Unbound
This relic grants a significant head start on Osty's HP at the beginning of every combat, ensuring Sacrifice provides a respectable amount of Block even in the early turns before other Summon cards are played.
Afterlife
As a high-value Summon card, Afterlife is a core building block for increasing the Max HP pool that Sacrifice requires to become a reliable late-game defensive solution.