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Every 3 times you apply Poison, deal 11 damage to ALL enemies.
Outbreak is a premier AoE scaling tool for Poison decks that rely on frequent, small applications of Poison rather than single large stacks. It excels in encounters with multiple enemies where cards like Envenom or Noxious Fumes can trigger the 11-damage burst multiple times per combat.
Bouncing Flask
Bouncing Flask applies Poison three times in a single play, which immediately satisfies the requirement for an Outbreak trigger. This provides high-value burst damage alongside the damage-over-time application.
Corrosive Wave
This card applies Poison to all enemies every time you draw, which can trigger Outbreak repeatedly during a single turn if you have sufficient draw power. It turns cycling your deck into a source of massive, consistent AoE damage.
Envenom
Envenom causes every unblocked attack to apply Poison, allowing Shiv-heavy decks to trigger Outbreak multiple times per turn. This synergy allows the Silent to maintain high single-target pressure while Outbreak handles secondary targets.
Noxious Fumes
By applying Poison to every enemy at the start of the turn, Noxious Fumes provides a reliable, passive way to stack Outbreak triggers. In encounters with multiple enemies, this guarantees at least one AoE proc every turn without spending additional energy.
Twisted Funnel
This relic applies Poison to all enemies at the start of combat, immediately providing multiple applications if several enemies are present. This jumpstarts Outbreak's damage, helping the Silent deal with early-combat threats in multi-enemy floors.