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Gain 1 Block.
Permanently increase this card's Block by 3.
Genetic Algorithm is a long-term investment card that should be played as early as possible in every combat to maximize its permanent block growth. It starts as a weak defensive option but eventually becomes an essential tool for surviving massive single-hit attacks in the late game.
Echo Form
Echo Form allows the first card played to be cast twice, which triggers the permanent block increase twice in a single combat. This effectively doubles the speed at which the card scales for the rest of the run.
Hologram
Since Genetic Algorithm must be played to scale, Hologram provides a safety net if the card is discarded or needs to be retrieved from the discard pile. It ensures you never miss an opportunity to increase the card's permanent block value during a fight.
Dolly's Mirror
This relic allows you to create a second copy of a Genetic Algorithm that has already been partially scaled. Having two copies of a massive block-generating card significantly trivializes late-game defensive requirements.
Toxic Egg
As a Skill, Genetic Algorithm will automatically be upgraded when added to the deck if you possess this relic. Upgraded versions typically scale faster or provide a higher base, making the card efficient much earlier in the run.